Project A2

2022: 

Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts

Bettina Groetsch, Elisabeth Schachtschabel, Philipp Tripal, Benjamin Schmid, Ana-Suncana Smith, Georg Schett, Aline Bozec

Epithelial HIF2α expression induces intestinal barrier dysfunction and exacerbation of arthritis

Jinming Wen, Pang Lyu, Iris Stolzer, Jin Xu, Andreas Gießl, Zhen Lin, Darja Andreev, Katerina Kachler, Rui Song, Xianyi Meng, Shan Cao, Giuliana Guggino, Francesco Ciccia, Claudia Günther, Georg Schett, Aline Bozec

2021: 

The Transcription Factor FRA-1/AP-1 Controls Lipocalin-2 Expression and Inflammation in Sepsis Mode

Shan Cao, Anne Schnelzer, Nicole Hannemann, Georg Schett, Didier Soulat, Aline Bozec

Systemic PPARγ Antagonism Reduces Metastatic Tumor Progression in Adipocyte-Rich Bone in Excess Weight Male Rodents

Anastasia Gaculenko, Gasper Gregoric, Vanessa Popp, Lisa Seyler, Mark Ringer, Katerina Kachler, Zhengquan Wu, Wadim Kisel, Christine Hofbauer, Lorenz C Hofbauer, Michael Uder, Georg Schett, Tobias Bäuerle, Aline Bozec

2020: Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis

Darja Andreev, Mengdan Liu, Katerina Kachler, Mireia Llerins Perez, Philipp Kirchner, Julia Kölle, Andreas Gießl, Simon Rauber, Rui Song, Oliver Aust, Anika Grüneboom, Arnd Kleyer, Juan D Cañete, Arif Ekici, Andreas Ramming, Susetta Finotto, Georg Schett, Aline Bozec

Environmental Microbial Factors Determine the Pattern of Inflammatory Lesions in a Murine Model of Crohn’s Disease-Like Inflammation

Iris Stolzer, Valentina Kaden-Volynets, Barbara Ruder, Marilena Letizia, Miriam Bittel, Philipp Rausch, Marijana Basic, André Bleich, John F Baines, Markus F Neurath, Stefan Wirtz, Carl Weidinger, Stephan C Bischoff, Christoph Becker, Claudia Günther

2019:

Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn’s Disease.

Günther C, Ruder B, Stolzer I, Dorner H, He GW, Chiriac MT, Aden K, Strigli A, Bittel M, Zeissig S, Rosenstiel P, Atreya R, Neurath MF, Wirtz S, Becker C.

How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis

Ulrike Steffen, Georg Schett, and Aline Bozec